Interaction of Imipenem and Tigecycline against Carbapenem-Resistant Acinetobacter baumanii: The Relativity of Synergism
نویسندگان
چکیده
منابع مشابه
In vitro Comparison of Anti-Biofilm Effects against Carbapenem-Resistant Acinetobacter baumannii: Imipenem, Colistin, Tigecycline, Rifampicin and Combinations
BACKGROUND Multi-drug resistant (MDR) Acinetobacter baumannii has emerged as one of the most important nosocomial pathogens. In addition to the diverse resistance mechanisms, some A. baumannii strains are known to have biofilm-producing capacity, thereby decreasing antibiotic effectiveness. MATERIALS AND METHODS This study was designed to assess biofilm-producing capacity of three different M...
متن کاملWhat remains against carbapenem-resistant Enterobacteriaceae and Acinetobacter spp? Evaluation of Tigecycline and Colistin
Nosocomial infection by multi-drug resistant bacteria (MDR) e.g: extended-spectrumBeta-lactamase(ESBL) producing Enterobacteriaceae, Acinetobacter baumannii and carbapenem-resistant Enterobacteriaceae (CRE) is increased worldwide, with major burden due to limited choices of antibiotics (Peleg & Hooper, 2010, Magiorakos et al.,2012). Tigecycline (TIG) and Colistin (COL) are examples of the few d...
متن کاملIn vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii.
This survey was conducted to evaluate the in vitro activity of tigecycline against 50 isolates of multidrug-resistant (MDR) Acinetobacter baumannii. Isolates of A. baumannii were resistant to ciprofloxacin, chloramphenicol, imipenem, levofloxacin, piperacillin and piperacillin-tazobactam, but were always susceptible to colistin. MICs of tigecycline were determined by E-test in Mueller-Hinton ag...
متن کاملIn vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii and selection of tigecycline-amikacin synergy.
Polymyxin B, minocycline, and tigecycline were the most potent of 10 antibiotics against 170 isolates of multidrug-resistant Acinetobacter baumannii. In time-kill studies, the exposure of a highly tigecycline-resistant isolate to tigecycline resulted in enhanced susceptibility to amikacin and synergistic bactericidal activities of the two drugs.
متن کاملCarbapenem-resistant Acinetobacter baumannii
To the editor: We read with interest the paper of Hrabák et al. [1] on the isolation of a blaNDM-1-carrying Acinetobacter baumannii strain. However, although the authors believed to be the first in the Czech Republic to report on a New Delhi metallo-beta-lactamase-1 (NDM-1)-producing bacterium, there have been other reports on the same A. baumannii strain in the country [2,3]. Here, we would li...
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ژورنال
عنوان ژورنال: Sains Malaysiana
سال: 2015
ISSN: 0126-6039
DOI: 10.17576/jsm-2015-4407-19